Disease Report- Syphilis

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Submitted By roshni2212
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Syphilis
By: Roshni Patel

Transmission: * Syphilis is primarily transferred through sexual contact. This can be from open sores around or inside the gentiles or mouth and the mucous membrane (1). * The disease can also be spread from the mother to the fetus via the placenta in utero, this normally occurs during the late stage of pregnancy (3). * Human to human contact thus far is the only known way to acquire syphilis (7).

Reservoirs: * The bacterium lives in the human genital tract of infected males and females (5).
Etiologic Agent:

* Treponema Pallidum (5).

Microorganism General Characteristics:

* T. pallidum is a spirochete, which is a type of bacteria that is helically shaped and the gram stains are usually negative. This pathogen is only found in humans and does not naturally occur in other species. This microorganism is transmitted through penetration of the spirochetes through mucous membranes or abrasions on the skins surface. T. pallidum is easily broken down which causes it to lack the capability to survive of dry, disinfected surfaces (3).

* Silver imprinting methods can be used to view the bacterium by dark field microscopy. The flagella of the spirochete move in the periplasmic space along the flagella bundle, this causes the bacterium to move in a corkscrew structure. The bacterium promptly rotates along its longitudinal axis and then bends and snaps to its full length. The bacterium can range in cell size from 6 to 15 micrometers long and 0.1 to 0.2 micrometers wide. Due to the bacterium’s limited temperature and pH ranges, it is unable to be transmitted by public surfaces. The typical temperature range is between 30 to 37 degrees Celsius and the ideal pH is 7.2 to 7.4, a neutral environment (5).

Identification Key Tests: * Serologic testing is the standard method of testing for syphilis…...

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